78 articles - From Friday Feb 06 2026 to Friday Feb 13 2026
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
| Am J Clin Nutr |
|---|
| Addressing Micronutrient Requirements in Type 2 Diabetes: An International Consensus Report.
The plan for this consensus has been registered on the Practice Guideline Registration for Transparency (PREPARE) (Registration Number: PREPARE-2025CN1178). The expert panel proposed potential target serum levels, screening strategies, and micronutrient supplementation for people with T2D and that personalized nutritional strategies integrating individual characteristics, genetic information, and gut microbiota represent key areas for future research. |
meta-analyses and systematic reviews
| Am J Clin Nutr |
|---|
| Fiber Intake and Laxation in People With Normal Bowel Function: A Systematic Review.
RCTs support small to modest effects of dietary fiber on laxation in generally healthy people with normal bowel function. Low solubility and low fermentability fibers yielded the strongest effects. Future studies should better characterize fiber properties, assess wider ranges of fiber doses, and comprehensively report participants' total and background fiber intake. Registry number Registered with PROSPERO (CRD42024522380). |
| Inflamm Bowel Dis |
| Advanced therapies for inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and meta-analysis.
Advanced therapies show efficacy and comparable safety in IBD-PSC. The study findings are limited by significant heterogeneity and further prospective studies with standardized endpoints are needed. |
| Systematic review and meta-analysis of childhood exposure to antibiotics and the subsequent risk of IBD.
While causal interpretation should be cautious, childhood exposure to antibiotics was associated with an increased risk of later IBD, particularly for CD. |
| Pancreas |
| Intrapancreatic Fat Deposition and Risk of Post-ERCP Pancreatitis: A Systematic Review and Meta-analysis.
IPFD was a significant contributor to the overall risk of PEP and its severe form. These findings highlight pancreatic fat as a potentially modifiable preprocedural risk factor, indicating the need for further validation and consideration of targeted prophylactic strategies to prevent post-ERCP pancreatitis. |
| Pancreatology |
| High prevalence of anxiety and depression among patients with acute and chronic pancreatitis: A systematic review and meta-analysis.
Our findings reveal a notably high prevalence of depression and anxiety in pancreatitis, exceeding global averages and rates seen in other GI disorders. These findings warrant routine psychological screening, ongoing follow-up, and the integration of mental health professionals into multidisciplinary care teams are therefore warranted. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
|---|
| Associations between breastfeeding, childhood BMI and pubertal onset: findings from a prospective cohort study.
Exclusive breastfeeding and longer breastfeeding duration were associated with later onset of puberty in boys and girls. Prepubertal BMI did not mediate the observed associations. |
| Blood micronutrients modified associations between blood heavy metals and cognitive decline in a nationally representative cross-sectional study.
This study revealed that the neurodegenerative influence of heavy metals is more pronounced in individuals with lower micronutrient status. If the results of the present study are confirmed by future studies, reducing heavy metal exposure and improving micronutrient status may offer a novel and practical strategy for preventing cognitive decline and dementia. |
| Changes in dietary sodium knowledge, attitudes and behaviours among Canadian adults in 2011 and 2024: A repeated cross-sectional study.
Many indices of sodium-related KAB deteriorated from 2011 to 2024 among Canadian adults, despite their continued concern about sodium intake. These findings highlight a widening knowledge-to-action gap and reinforce the need for comprehensive public health efforts to support population-wide dietary sodium reduction. |
| Comparison of food processing classification frameworks in the National Health and Nutrition Examination Survey (NHANES) 2017 - 2018.
Despite differences in classification criteria across systems, associations with nutrients, sociodemographic, and cardiometabolic parameters were consistent. A standardized classification system is needed to ensure a unified understanding of ultra-processed food and its health implications. |
| Folic acid fortification of iodized salt improves the folate status of non-pregnant adult Ethiopian females and does not impair their iodine status: a community-based, household-randomized, dose-response trial.
FA fortification of salt is an effective and safe method to improve women's folate status and thereby reduce the risk of NTD-affected pregnancies. |
| Foods of concern, cardiopreventive medication use and risk of cardiovascular diseases: a prospective study in the CARTaGENE cohort.
In individuals with hypertension or hypercholesterolemia, lower consumption of UPFs or foods with FOPS was similarly associated with lower CVD risk, independent of concomitant medication use. |
| Gestational diabetes, human milk oligosaccharide (HMO) concentrations, and their links to infant weight gain and the gut microbiome in a United States observational cohort.
Mothers with a GDM diagnosis had higher milk concentrations of LNFP III and 6'SL, and 6'SL was in turn associated with increased infant growth rate, but neither HMO was associated with differential infant gut microbial abundances. The results suggest that the link between 6'SL and faster infant growth, if causal, occurs via mechanisms independent of the infant gut microbiome. Clinical trials registration The study is registered with ClinicalTrials.gov under NCT03301753. |
| Health-related quality of life, compliance and sustained adherence on a Low-Carbohydrate High-Fat diet compared with a High-Carbohydrate Low-Fat diet in people with type 2 diabetes.
HRQoL improved in both dietary intervention groups with no difference between groups. Dietary compliance was associated with improved HRQoL and may play a role in sustained adherence to the LCHF diet. Clinical trial registry number ClinicalTrials.gov (NCT03068078), |
| Ingestion of diverse protein-rich whole-foods result in similar post-exercise whole-body and myofibrillar protein synthesis rates compared with a more isolated protein source in young adults.
The ingestion of a variety of protein-rich whole-foods or a more isolated protein source (egg whites) following lower body exercise results in comparable MyoPS rates, though a greater whole-body net protein anabolism was achieved with egg whites. |
| Meal fatty acid metabolism is associated with long-term weight gain in women - a retrospective cohort study.
The finding that weight change is correlated with dietary fatty acid metabolism for adult, non-obese females suggests that inter-individual variations in how women process dietary fat can influence long-term energy balance. Clinical trial registration |
| Omega-3 polyunsaturated fatty acid levels in childhood prospectively associate with academic performance beyond a healthy diet: findings from the multi-ethnic Asian GUSTO cohort study.
Higher plasma total n-3 LC-PUFA and DHA were prospectively associated with better academic performance in primary school children, but the relationship with DHA was modulated by an unhealthy dietary pattern. The results suggest that beyond DHA, total n-3 LC-PUFA status plays a significant role in the cognitive development of children. |
| Plasma n6 polyunsaturated fatty acid levels and risk for dementia: A prospective observational study from the UK Biobank.
We observed heterogeneous associations between different types of n-6 PUFAs and risk of dementia, supporting the increasing view that n-6 PUFAs should not be treated homogeneously. Future research should investigate whether dietary LA (which drives plasma LA levels) may help reduce risk for dementia. Registration This research has been conducted using the UK Biobank Resource under Application Number 85092. |
| Predictive equations commonly used in clinics underestimate resting energy expenditure compared with whole-room indirect calorimetry in colorectal cancer survivors.
This study was registered at clinicaltrials. gov as NCT01570010 ( |
| Remission of impaired glucose tolerance by anthocyanin supplementation: a randomized, double-blind, and placebo-controlled trial.
Anthocyanin supplementation could significantly reverse IGT by improving insulin sensitivity. The reduction of skin AGEs by anthocyanins might play a critical role in the dietary management of IGT. |
| Inflamm Bowel Dis |
| Dynamic changes in clinical response to corticosteroids in ulcerative colitis.
Corticosteroid response in UC is a dynamic phenomenon. Over a third of non-responders remain unresponsive in subsequent courses. Extraintestinal manifestations, corticosteroid type, and greater disease extension are associated with an increased likelihood of clinical response to corticosteroids. |
| Frequency of computed tomography scans in Crohn's disease patients in the emergency department.
Radiation exposure in Crohn's patients is higher than that of the general population, owing to multiple CT scans often performed acutely in the ED. Factors we assessed could not reliably predict urgent findings on CT and a significant percentage of patients had urgent findings. However, we identified a group with multiple CTs associated with barriers to healthcare. |
| Immunometabolism as a New Bimodal Therapeutic Concept in Inflammatory Bowel Disease and Immune-Mediated Inflammatory Disorders.
Preliminary clinical data support the potential utility of immunometabolic modulation, particularly in combination with existing therapies, to overcome the current therapeutic ceiling in clinical efficacy. Continued research is needed to validate the efficacy, safety, and mechanistic precision of immunometabolic agents across the spectrum of IMIDs. |
| Integrated long-term safety of 10-year ozanimod treatment: results from clinical trials in patients with moderate-to-severe ulcerative colitis or relapsing multiple sclerosis.
Long-term exposure to ozanimod is well tolerated in patients with moderate to severe UC or RMS, confirming the previously established safety profile of ozanimod. Clinical trial registry NCT01647516; NCT02435992; NCT02576717. |
| Integrating intestinal ultrasound into routine clinical care improves prediction of biochemical disease activity in pediatric inflammatory bowel disease.
Integrating IUS with clinical symptoms during routine clinic visits was superior to shPCDAI alone in predicting CD activity, and may potentially be superior to PUCAI for UC. Incorporating IUS into routine visits may accelerate treatment decisions, thereby advancing an improved point-of-care treat-to-target approach. |
| Long-term clinical and endoscopic outcomes of ulcerative colitis after liver transplantation: a multicenter cohort study on the use and safety of advanced therapies.
In most patients, clinical disease activity remains stable after LT. However, persistent moderate-to-severe mucosal inflammation is observed in a substantial subset during long-term follow-up. Advanced therapies, particularly vedolizumab, are being used more frequently in this setting and may offer disease control without a corresponding increase in infection risk. These findings underscore the need for individualized, interdisciplinary management and further prospective evaluation of treatment strategies in this population. |
| Nomenclature of therapies in inflammatory bowel disease: A journey through time and terminology.
Drawing on historical and current literature, as well as policy documents from the World Health Organization's international nonproprietary name expert group, this review charts the development and successive reforms of the naming scheme. As inflammatory bowel disease therapies continue to diversify, understanding this evolving nomenclature is increasingly important for safe prescribing and effective communication. |
| Persistence and safety of subcutaneous infliximab up to 1 year after switching from intravenous infliximab in pediatric inflammatory bowel disease: a multicenter real-world cohort study.
The largest documented PIBD cohort switching to SC-IFX to date showed high treatment persistence at 1 year, confirming SC-IFX as an effective and safe maintenance alternative to IV-IFX. |
| Persistent Abdominal Pain in Patients with Inactive Inflammatory Bowel Disease: A Clinical Conundrum.
Emerging evidence suggests that such pain may result from complex interactions involving visceral hypersensitivity, alterations in the enteric nervous system, central sensitization, dysregulation of the gut-brain axis, and psychosocial factors, rather than ongoing mucosal inflammation. This review explores the multifactorial pathophysiology underlying persistent abdominal pain in inflammatory bowel disease remission and highlights the need for a comprehensive, biopsychosocial approach to diagnosis and treatment. |
| Primary infliximab failure in pediatric colonic inflammatory bowel disease: Development of a proteomics predictive model using a prospective Canadian cohort.
A serum proteomics linear model on treatment-naïve serum best predicted PNR. Findings require external validation but suggest that the diagnostic/pretreatment window may be key to understanding biology central to effective drug sequencing. |
| Rapid symptomatic improvement with etrasimod in ulcerative colitis: a post-hoc analysis of the ELEVATE UC program.
In this post-hoc analysis, improvements in UC symptoms occurred in patients receiving etrasimod vs placebo from as early as day 2. These findings indicate a rapid onset of symptomatic effect with etrasimod treatment for moderately to severely active UC. numbers NCT03945188, NCT03996369. |
| Safety and outcomes of advanced IBD therapies in patients with HIV: a propensity-matched cohort analysis.
and relevance In this large multicenter cohort, AT use in HIV-IBD was rare but not associated with higher risks of infection, cancer, surgery, or death. These findings support the safety of AT in this population. |
| Stricture dynamics and prognosis during biologic therapy in ileal Crohn's disease: a real-world cohort.
The 6‑month stricture status, especially non-terminal ileal disease, carried prognostic significance. Because stricture dynamics did not differ across biologic classes, the presence of strictures alone should not constrain agent selection. |
| J Crohns Colitis |
| A Descriptive Comparison of Phase 3 Results and Head-to-Head Trials in Inflammatory Bowel Diseases.
Significant heterogeneity in trial design, populations and outcome reporting limits the predictive value of placebo-controlled trials. Randomized head-to-head trials remain essential for optimizing IBD therapeutic strategies. |
| Liver Transpl |
| A pilot, two-centre, sequential dose escalation safety study of alteplase with fresh frozen plasma during normothermic liver perfusion.
Portal delivery was found to be more straightforward than infusion into the hepatic artery cannula. The combination of alteplase with FFP appeared safe, with no bleeding complications. |
| A simple intraoperative score incorporating thromboelastometric parameters predicts early reoperation for bleeding after liver transplantation.
VEA demonstrated strong predictive value for early reoperation for bleeding after LT. The proposed risk score could facilitate the timely correction of coagulation and potentially improve clinical outcomes after LT. |
| An international survey of liver transplant business practices: Identifying best practices and areas for improvement.
While international concerns varied widely among LT centers, inadequate salary and center funding, low transplant and referral volumes, and staff retainment were persistent themes. Focusing on adopting region-specific best practices and developing transplant systems of care that focus on these elements is critical to provide optimal care to LT patients worldwide. |
| Benchmarking the real-world transplant benefit in unresectable colorectal liver metastases: A preliminary external validity assessment of the TransMet trial.
The findings of this first real-world assessment of the TransMet trial criteria and 5-year TB estimation in unresectable CRLM point to reasonable prognostic candidates and support evaluating the inclusion of CRLM in LT allocation models. We advocate expanded multicenter data to reach sufficient prognostic stratification through well-calibrated, highly discriminative studies. |
| Food environment as a determinant of Post-Transplant diabetes and regional variation in the United States.
LT recipients in counties with decreased access to healthy foods were significantly more likely to develop PTDM. Food environment accounted for a meaningful proportion of regional differences in PTDM. Identifying and addressing food insecurity among LT recipients may represent a modifiable pathway to improve long-term outcomes. |
| Heterogeneity in liver transplantation practices for critically ill patients with chronic liver disease in the U.S.
Adjusting for severity of illness, center volume of ICU LTs in the prior year was associated with a small but significant reduction in 1-year post-ICU LT mortality: aOR 0.96 per 5 ICU LTs (p<0.001). Expansion of LT for ICU candidates does not appear to threaten center-based metrics and may even offer important benefits to future candidates. |
| Social drivers of differences in hepatocellular carcinoma (HCC) stage of diagnosis, treatment and survival in a large, integrated healthcare system.
These findings highlight persistent inequities in HCC stage at diagnosis and survival, with API patients experiencing more favorable outcomes and individuals from socioeconomically deprived neighborhoods facing worse long-term survival. Efforts to reduce structural barriers and improve early detection are needed to narrow these disparities. |
| Strategies and outcomes of multiple bile duct reconstruction in living donor liver transplantation.
Duct-to-jejunum anastomoses offer a viable alternative with fewer complications for MBDs. Tailored strategies and technical refinements can mitigate the complications associated with MBD reconstruction. |
| Pancreas |
| Association of Pain with Healthcare Use and Indirect Burden in Pediatric Acute Recurrent and Chronic Pancreatitis.
Pediatric painful ARP/CP imposes substantial direct and indirect burden. Interventions targeting pain and disability may reduce healthcare use and improve functioning and family well-being. |
| Evaluation of Malignant Predictive in Pancreatic Intraductal Papillary Mucinous Neoplasm Using Diffusion-weighted Imaging and Apparent Diffusion Coefficient Values: A Comparative Analysis With Histopathology.
DWI and ADC mapping are valuable diagnostic tools for differentiating benign and malignant IPMNs. These modalities can complement existing diagnostic criteria, reduce unnecessary surgeries, and enhance clinical decision-making. |
| Home-based Transcutaneous Electrical Acustimulation (TEA) for the Treatment of Pain in Chronic Pancreatitis: A feasibility trial.
We found that TEA was feasible and acceptable for the treatment of painful CP. These results lay the groundwork for larger trials evaluating the efficacy of TEA in painful CP. |
| Pancreatology |
| Accelerated focused open necrosectomy-based step-cross versus conventional step-up approach in infected necrotizing pancreatitis.
The step-cross approach is a safe complementary strategy to the step-up approach, demonstrating trends toward lower mortality and reduced organ support requirements in selected INP patients. Nevertheless, these findings require validation through large-scale prospective studies. |
| Comparative outcomes analysis of Whipple procedure in dialysis-dependent patients: A propensity-matched study using NSQIP data.
Although dialysis patients undergoing PD face increased risks of mortality and complications, PD-specific complications were not affected. These findings offer valuable insights for patient counseling and surgeon awareness. |
| Long-term disease progression in pediatric acute recurrent and chronic pancreatitis: A report from INSPPIRE.
Prospective follow-up of children with ARP revealed nearly 1 in 5 progressed to CP, with a subset developing irreversible sequelae, and highlighted risk factors associated with progression including genetics, obstructive disease, and episode frequency. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Inflamm Bowel Dis |
|---|
| Clinical response for 12 months or more to the first advanced therapy in IBD decreases long-term risk of hospitalization: a spirited stride…. |
| J Crohns Colitis |
| Beyond the mucosa: intestinal ultrasound for post-endoscopic healing risk stratification in ulcerative colitis. |
| Pancreas |
| Advances in Glucocorticoid Therapy for Acute Pancreatitis: A Review.
GCs exhibit potential in the management of AP by modulating inflammatory pathways and immune responses. Their use necessitates thorough risk assessment. Large-scale clinical trials are essential to establish standardized protocols, optimal dosing regimens, and patient selection criteria for GCs therapy in AP. |
| Complications of Pancreatitis-Knowledge Gaps and Research Opportunities: A Workshop Summary.
Genetic testing in pancreatitis is likely to inform any research related to the complications of CP, but low penetrance of disease, poor genotype-phenotype associations, and health disparities that impact the use of testing across centers currently limit its clinical utility for al patients. Genetic testing remains critical in certain populations with CP and should be incorporated into research whenever possible to inform much-needed disease progression prediction models. |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Am J Clin Nutr |
|---|
| New International Classification of Diseases-11 Code for Diagnosis of Adult Undernutrition in Clinical Settings. |
| Inflamm Bowel Dis |
| Clinical outcomes in pregnancy after ileal pouch-anal anastomosis for ulcerative colitis. |
| Repeated Administration of Carotegrast Methyl Maintained Clinical Remission With Difficult-to-Treat Ulcerative Colitis. |
| Reply: "The Missing Link: Fusobacterium nucleatum in Postileectomy Colorectal Carcinogenesis". |
| Steroid response in ulcerative colitis is not binary: learning from dynamic trajectories. |
| Liver Transpl |
| Harmonizing therapeutic hierarchy and transplant benefit in hepatocellular carcinoma management. |
| Intraoperative thromboelastometry: Can we predict early reoperation for non surgical bleeding ? |
| Letter to the Editor: The application of generative artificial intelligence in liver transplantation weight trajectory. |
| Letter to the editor: Estimating the cost of liver transplantation. |
| Letter to the editor: Reconsidering fibrinolytic assessment and hemostatic management in liver transplantation. |
| Newly diagnosed pulmonary arterial hypertension following liver transplantation: Insights from a multicenter case series. |
| Radiating an advantage: Comparative outcomes in transarterial locoregional therapies favor radioembolization bridging for transplant candidates with hepatocellular carcinoma. |
| Reply: Estimating the cost of liver transplantation. |
| Reply: Reconsidering fibrinolytic assessment and hemostatic management in liver transplantation. |
| Reply: The application of generative artificial intelligence in liver transplantation weight trajectory. |
| Pancreas |
| Clinical Characteristics of Acute and Chronic Pancreatitis in Children and Impact of Obesity. |
| Post-Pancreatectomy Diabetes: Is it Steatosis or the Standard Adjuvant Therapy? |
| Pancreatology |
| Acute pancreatitis in relation to SARS-CoV-2 vaccination and infection: A nationwide cohort study in Sweden. |
| Enhancing multidisciplinary tumor board decision-making in pancreatic cancer using cinematic rendering. |
| Feasibility of sham vs. pancreatic endotherapy for painful chronic pancreatitis: Lessons from a randomized trial. |
| Increased risk of developing diabetes following a sentinel episode of acute pancreatitis in patients with obesity: A propensity matched population study. |
| Prospective observational study on the impact of hepatic steatosis, hepatic fibrosis, and metabolic syndrome on the outcome of patients with acute pancreatitis. |
Letters to the editors and authors’ replies
| Am J Clin Nutr |
|---|
| Beyond prediction: interpreting metabolic signatures of Mediterranean diet in rheumatoid arthritis. |
| Consider the sagittal abdominal diameter for estimating visceral adipose tissue. |
| The "growth-programming dissociation window": why early protein trials may be structurally blind to metabolic risk. |
| Pancreatology |
| Spontaneous cysto-biliary communication in walled-off necrosis of the pancreas. |